BTC $56772.0455
ETH $3229.2692
BNB $393.0365
SOL $106.6536
stETH $3224.6597
XRP $0.5621
ADA $0.6137
AVAX $38.6261
DOGE $0.0960
TRX $0.1415
wstETH $3753.2551
DOT $8.0619
LINK $18.8685
WETH $3222.5827
MATIC $1.0217
UNI $10.5943
WBTC $56672.8182
IMX $3.2827
ICP $12.8638
BCH $296.0952
LTC $73.4211
CAKE $3.1049
LEO $4.3751
ETC $27.6986
FIL $7.7121
KAS $0.1681
RNDR $7.1714
DAI $0.9992
HBAR $0.1085
ATOM $10.9103
INJ $37.3719
VET $0.0480
TON $2.1032
OKB $51.5043
FDUSD $1.0007
LDO $3.4620
STX $3.0518
XMR $133.5710
ARB $1.8885
XLM $0.1189
GRT $0.2844
TIA $16.9400
NEAR $3.9210
ENS $21.6903
MKR $2126.5962
WEMIX $2.0704
APEX $2.3723
BTC $56772.0455
ETH $3229.2692
BNB $393.0365
SOL $106.6536
stETH $3224.6597
XRP $0.5621
ADA $0.6137
AVAX $38.6261
DOGE $0.0960
TRX $0.1415
wstETH $3753.2551
DOT $8.0619
LINK $18.8685
WETH $3222.5827
MATIC $1.0217
UNI $10.5943
WBTC $56672.8182
IMX $3.2827
ICP $12.8638
BCH $296.0952
LTC $73.4211
CAKE $3.1049
LEO $4.3751
ETC $27.6986
FIL $7.7121
KAS $0.1681
RNDR $7.1714
DAI $0.9992
HBAR $0.1085
ATOM $10.9103
INJ $37.3719
VET $0.0480
TON $2.1032
OKB $51.5043
FDUSD $1.0007
LDO $3.4620
STX $3.0518
XMR $133.5710
ARB $1.8885
XLM $0.1189
GRT $0.2844
TIA $16.9400
NEAR $3.9210
ENS $21.6903
MKR $2126.5962
WEMIX $2.0704
APEX $2.3723
  • Catalog
  • Blog
  • Tor Relay
  • Jabber
  • One-Time notes
  • Temp Email
  • What is TOR?
  • We are in tor
  • Market for psychoactive substances in 2022. Part 3


    In a forensic report published on July 13, 2022, researchers from the American company Aegis Sciences Corporation, which specializes, among other things, in forensic medical examination, named the substances that were most often found in confiscated samples in the first half of 2022.

    Stimulants

    • In the fourth quarter of 2021, Eutylone (also known as bk-EBDB or N-ethylbutanamine), a stimulant and empathogen from the family of synthetic substituted cathinones, was the most frequently seized. It is structurally and pharmacologically similar to MDMA, methylone, and pentylone. Consumers describe the action as mild, clear, euphoric, serotonergic stimulation. By January 2022, Eutylone ceased to dominate the market, losing the palm to Pentylone.
    • Pentylone (also known as bk-MBDP and methyl​enedioxy​pentedrone) is a substituted cathinone stimulant synthesized in the 1960s. Acts as a norepinephrine and dopamine reuptake inhibitor and serotonin releasing agent. The effects are reminiscent of MDMA.
    • The third most commonly seen synthetic stimulant in 2022, after Eutylone and Pentylone, is α-PiHP, an analogue of alpha-PVP.

    The above substances are followed by:

    • Butylone (βk-MBDB) is an entactogen, psychedelic and psychostimulant belonging to the class of phenethylamines. It was first synthesized in the second half of the 1960s.
    • Dibutylone (bk-DMBDB) is a stimulant of the amphetamine, phenethylamin, and cathinone classes. Structurally similar to butylone.
    • N-Ethylhexedrone is a cathinone class stimulant that acts as a norepinephrine and dopamine reuptake inhibitor. It was synthesized in the first half of the 1960s.
    • N-Ethylheptedrone is a stimulant of the class of substituted cathinones, a homologue of ethcathinone, N-ethylbuphedrone and N-ethylhexedrone.

    Finally, among the most popular stimulants of 2022 were fluorinated analogues of amphetamine and methylphenidate:

    • 3-Fluoroamphetamine is a class of amphetamine that acts on par with methamphetamine as a ьonoamine releasing agent, but is more selective for dopamine and norepinephrine than for serotonin.
    • 4-Fluoroamphetamine is an analogue of 3-Fluoroamphetamine and is an agonist of both dopamine and serotonin receptors.
    • 4-Fluoromethamphetamine (4-FMA) is a stimulant structurally related to methamphetamine and 4-Fluoroamphetamine.
    • 3-Fluoromethamphetamine (3-FMA) is an entactogen and stimulant.

    Opioids

    Popular opioids in 2022 include various substances of different classes - analogues of fentanyl, "Nitazenes" and "utopioids".

    • As of June 2022, the opioids fluorofentanyl and despropionyl-p-fluorofentanylwere the most frequently detected, followed by the opioid analgesic isotonitazene in third place (more effective than fentanyl), and benzylfentanyl in fourth place.
    • In fifth place is the opioid analgesic metonitazene. It is 100 times more effective than morphine when injected and 10 times more effective when taken orally.
    • In sixth place is another analogue of fentanyl, Valerylfentanyl. All of the above substances were synthesized in the last century and appeared on the market in the past, although they did not receive mass distribution.

    In contrast, four opioid analgesics entered the market en masse only in 2022:

    • one of them is the utopioid U-47700. Structurally, utopioids are not analogues of fentanyl. The name of these components comes from the name of the Upjohn company, which in the 1970s and 1980s studied their therapeutic potential. U-47700 is 10 times more potent than morphine.
    • other new opioids are cyclopropylfentanyl, Despropionyl meta-chlorofentanyl (analogues of fentanyl), and Protonitazene.

    Benzodiazepines 

    In 2022, Clonazolam, Flualprazolam, Bromazolam, Flubromazolam, Flubromazepam, Diclazepam, 3-Hydroxyphenazepam, Adinazolam, Deschloroetizolam received the greatest distribution.

    Hallucinogens and Dissociatives 

    Four new dissociatives were first identified in 2022:

    • 3F-PC;
    • 2-fluoro-deschloroketamine;
    • 2-fluoro-deschloronorketamine;
    • deschloro-N-ethyl-Ketamine.

    Popular new psychoactive substances not in the above categories

    • Xylazine is a veterinary drug that has a sedative, analgesic, anesthetic and muscle relaxant effect.
    • 4-Hydroxy Xylazine is a metabolite of Xylazine.
    • Tianeptine is an atypical tricyclic antidepressant well known under the brand name Coaxil.
    • Phenibut is a derivative of γ-Aminobutyric acid, a structural analogue of Gabapentin and Baclofen.

    These NPSs are also not literally new - they have been well known for a long time. The same Phenibut. However, they became widespread only in 2022.

    Thus, we see that worldwide the market for new psychoactive substances is growing at a rapid pace, not only in terms of quantity, but also in terms of diversity.


    All information is presented for informational purposes only and does not call for action!

    Author DeepWeb
    Ransomware revenue plummets
    Iranian and Russian hackers use phishing attacks against British politicians

    Comments 0

    Add comment